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Top Southeast Minnesota hotels

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $172 total per night from Jul 9 to Jul 10
$172 total
Jul 9 - Jul 10
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"The good: Clean room, comfortable bed, very kind staff, great breakfast, convenient parking garage. The bad: Wall outlets in the room were all very loose and nothing would stay plugged in (the weight of the plug would cause it to fall out). There were no bath towels in the room (I assume the cleaning ..."

Reviewed on Jul 1, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Treasure Island Resort & Casino

Treasure Island Resort & Casino

3 out of 5
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Jul 13 to Jul 14
$112 total
Jul 13 - Jul 14
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
"Friendly help."

Reviewed on Jul 5, 2026

Opens in a new windowTreasure Island Resort & Casino
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Jul 12 to Jul 13
$131 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"Clean room . Basic breakfast. Friendly staff."

Reviewed on Jul 5, 2026

Opens in a new windowCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

3 out of 5
900 Bruski Dr Winona MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $134 total per night from Jul 6 to Jul 7
$134 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The room had not been cleaned and it was 8:00 pm"

Reviewed on Jun 30, 2026

Opens in a new windowExpress Suites Riverport Inn & Suites
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $148 total per night from Jul 31 to Aug 1
$148 total
Jul 31 - Aug 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Staff were always friendly and helpful. Hot tub and pool were a plus for me. Did not need to go outside for any of my appointments at Mayo Clinic. Easy access to everything. Lord Essex restaurant has a great breakfast. Highly recommend the Kahler Grand Hotel."

Reviewed on Jul 3, 2026

Opens in a new windowKahler Grand Hotel
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Jul 12 to Jul 13
$91 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
"Clean room and entire hotel was clean! Great breakfast! Staff are wonderful!"

Reviewed on Jul 5, 2026

Opens in a new windowBest Western Rochester Hotel Mayo Clinic Area/St. Mary's
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Jul 6 to Jul 7
$160 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Room was clean. Staff was hopeful. Complementary breakfast was good. Parking space appreciated and rate was not terrible. However, it is a very tight lot."

Reviewed on Jul 3, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Jul 6 to Jul 7
$97 total
Jul 6 - Jul 7
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"It was an OK stay for the value. Pricepoint for the Two Queen Studio Kitchenette was great. The room we had, the stovetop was 2 burners right by the sink, did not use those cause of preference. Was not appealing to use. Fridge was full size and great and we made use of that. Microwave was standard. ..."

Reviewed on Jul 4, 2026

Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jul 12 to Jul 13
$87 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel's 3 indoor pools and gym are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"They help make your stay quiet and relaxing. It’s very clean and staff is friendly and helpful. I was going to Mayo and the shuttle is very nice and convenient so you don’t have to pay or drive down there. I’ve stayed at this location several times and I always go back because they take care of the ..."

Reviewed on Jul 5, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Minnesota hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeast Minnesota hotel reviews by fellow wanderers

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