Book Hotels in Southeast Minnesota, MN
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Top Southeast Minnesota hotels
Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Nov 27 to Nov 28
$128 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Clean and nice hotel. Excellent breakfast."
Reviewed on Nov 13, 2026
Treasure Island Resort & Casino
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $104 total per night from Nov 22 to Nov 23
$104 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
"Got there at 4 for check in, check in process took 15-20 minutes and room was not ready. Told they will text when the room is ready. 45 minutes later room was still not ready they switched rooms to a different tower and the walk was long. Long walk already from the parking lot. Never saw a shuttle ..."
Reviewed on Nov 13, 2026
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Nov 14 to Nov 15
$131 total
Nov 14 - Nov 15
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"I love the swimming pool"
Reviewed on Nov 13, 2026
Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $178 total per night from Nov 26 to Nov 27
$178 total
Nov 26 - Nov 27
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Location and staff are wonderful"
Reviewed on Nov 13, 2026
AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Dec 6 to Dec 7
$84 total
Dec 6 - Dec 7
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"Breakfast was good simple selections. Nice that they had fruit and yougart not everyone enjoys eggs. Room was clean. Beds fairly comfortable. Ice machines did not have ice. Food was with in walking distance to restaurant/bar connected."
Reviewed on Nov 13, 2026
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $165 total per night from Dec 12 to Dec 13
$165 total
Dec 12 - Dec 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Very convenient to Mayo Clinic using subway access from hotel. No need to walk outside."
Reviewed on Nov 13, 2026
Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Dec 13 to Dec 14
$84 total
Dec 13 - Dec 14
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"Old place. Rooms were decent and show some updating. Common areas real run down. Hot tub was non-operational and that was a big reason why I booked the stay."
Reviewed on Nov 11, 2026
Express Suites Riverport Inn & Suites
900 Bruski Dr Winona MN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Dec 6 to Dec 7
$123 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Brentwood Inn & Suites
123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $138 total per night from Nov 14 to Nov 15
$138 total
Nov 14 - Nov 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
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See all available properties in Southeast Minnesota
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Minnesota hotels
Red Carpet Inn Rochester
2214 South Broadway Rochester MN
$63 nightly
The price is $73 total per night from Nov 14 to Nov 15
$73 total
Nov 14 - Nov 15
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southeast Minnesota with star-rating
Check Southeast Minnesota Hotels by Star Rating
4 Star Hotels
7 properties
Recent Southeast Minnesota hotel reviews by fellow wanderers
Kahler Grand Hotel
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Location and staff are wonderful"
A verified traveler stayed at Kahler Grand Hotel
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